AN INTRODUCTION OF REFERENCES (READ IN FULL TEXT) TO HELP CONSTRUCT ddd MODELS
Adams A, Dolan P, Hutton W, Porter R Diurnal changes in spinal mechanics and their clinical significance. The Journal of Bone and Joint Surgery 1990;72B:266-70.
Adams M, Dolan P Recent advances in lumbar spinal mechanics and their clinical significance. Clinical Biomechanics 1995;10:3-19.
Adams M, Freeman B, Morrison H, Nelson W, Dolan P Mechanical initiation of intervertebral disc degeneration. Spine 2000;25:1625-36.
Albert H, Kjaer P, Jensen T, Sorensen J, Bendix T, Manniche C Modic changes, possible causes and relation to low back pain. Medical Hypotheses 2007 Article in press.
Alexander L, Hancock E, Agouris I, Smith F, MacSween A The response of the nucleus pulposus of the lumbar intervertebral discs to functionally loaded positions. Spine 2007;32:1508-12.
Althoff I, Brinckmann P, Frobin W, Sandover J, Burton K An improved method of stature measurement for quantitative determination of spinal loading: application to sitting postures and whole body vibration. Spine 1992;17:682-93.
Anjarwalla N, Brown L, McGregor A The outcome of spinal decompression surgery 5 years on. Eur Spine J 2007;16:1842-7.
Auerbach J, Johannessen W, Borthakur A, Wheaton A, Dolinskas C, Balderston R, Reddy R, Elliot D In vivo quantification of human lumbar disc degeneration using T1 weighted magnetic resonance imaging. Eur Spine J 2006;15:S338-44.
Baldwin N Lumbar disc disease: the natural history. Neurosurg Focus 2002;13:1-6.
Battie M, Videman T Lumbar disc degeneration: epidemiology and genetics.
Beach T, Parkinson R, Stothart P, Callaghan J Effects of prolonged sitting on the passive flexion stiffness of the in vivo lumbar spine. The Spine Journal 2005;5:145-54.
Belavy D, Richardson C, Wilson S, Rittweger J, Felenberg D Superficial lumbopelvic muscle overactivity and decreased cocontraction after 8 weeks of bed rest. Spine 2007;32:E23-9.
Benneker L, Heini P, Alini M, Anderson S, Ito K 2004 Young investigator award winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration. Spine 2005;30:167-73.
Bibby S, Jones D, Lee R, Yu J, Urban J The pathophysiology of the intervertebral disc. Joint Bone Spine 2001;68:537-42.
Bilgic S, Sonmez O, Odaci E, Colakoglu S, Kaplan S, Ergur H The new approach for the estimation of intervertebral disc volume using the Calavalieri principle and computed tomography. Clinical Neurology and Neurosurgery 2005;107:282-8.
Black K, McClure P, Polansky M The influence of different sitting positions on cervical and lumbar posture. Spine 1996;21:65-70.
Boos N, Weissbach S, Rohrbach H, Weiler C, Spratt K, Nerlich A Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in Basic Science. 2002;27:2631-44.
Botsford D, Esses S, Ogilvie-Harris D In vivo diurnal variation in intervertebral disc volume and morphology. Spine 1994;19:935-40.
Brisby H, Hammar I Thalamic actvation in a disc herniation model. Spine 2007;32:2846-52.
Brown M, Hukkanen M, McCarthy I, Redfern D, Batten, Crock H, Hughes S, Polak J Sensory and sympathetic innervation of the vertebral endplate in patinets with degenerative disc disease. J Bone and Joint Surg. 1997;79:147-53.
Buckwater J Spine update: aging and degeneration of the human intervertebral disc. Spine 1995;20:1307-14.
Bullough P The role of joint architecture in the etiology of arthritis. Osteoarthritis Cartilage 2004;12:S2-9.
Callaghan J, McGill S Low back joint loading and kinematics during standing and unsupported sitting. Ergonomics 2001;44:280-94.
Cao P, Kimura S, Macias B, Ueno T, Watenpaugh D, Hargens A Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest. 2005;99:39-44.
Cavanaugh et al. Pain Generation in Lumbar and Cervical Facet Joints. J Bone Joint Surg Am. 2006; 88: 63-67.
Cheung J, Zhang M, Chow D Biomechanical responses of the intervertebral joints to static and vibrational loading: a finite element study. Clinical Biomechanics 2003;18:790-799.
Claus A, Hides J, Moseley G, Hodges P Sitting versus standing: does the intradiscal pressure cause disc degeneration or low back pain? Journal of Electromyography and Kinesiology 2007 Mar.
Cook G, McGill S Spinal shrinkage during repetitive controlled torsional, flexion and lateral bend motion exertions. Ergonomics 2001;44:373-81.
Court C, Chin J, Liebenberg E, Colliou O, Lotz J Biological and mechanical consequences of transient intervertebral disc bending. Eur Spine J 2007;16:1899-1906.
Court C, Colliou O, Chin J, Liebenberg E, Bradford D, Lotz J The effect of static in vivo bending on the murine intervertebral disc. The Spine Journal 2001;1:23-45.
Cramer G, Darby S Spine, Spinal Cord, and ANS;2nd edition Elsevier Mosby Inc 2005.
Danielson B, Willen J Axially loaded magnetic resonance image of the lumbar spine in asymptomatic individuals. Spine 2001;26:2601-6.
Deursen L, Deursen D, Snijders C, Wilke H Relationship between everyday activities and spinal shrinkage. Clinical Biomechanics 2005;20:547-50.
Duncan J Cell Deformation and Micromechanical Environment in the Intervertebral Disc Bone Joint Surg Am.2006; 88: 47-51.
Edgar M The nerve supply of the lumber intervertebral disc . J Bone Joint Surg Br. 2007;89:1135-9.
El-Rich M, Shirazi A, Arjmand N Muscle activity, internal loads, and the stability of the human spin in standing postures:combined model and in vivo studies. Spine 2004;2633-42.
Ferguson S, Ito K, Nolte L Fluid flow and connective transport of solutes within intervertebral discs. Jounal of Biomechanics 2004;37:213-21.
Fredericson M, Lee S, Welsh J, Butts K, Norbash A, Carragee E Changes in posterior disc bulging and intervertebral foraminal size associated with flexion-extension movement: a comparison between L4–5 and L5–S1 levels in normal subjects The Spine Journal 2001;1:10–17.
Freemont A, Peacock T, Goupille P, Hoyland J, O’Brien J, Jayson M Nerve ingrowth into diseased intervertebral disc in chronic back pain. The Lancet 1997; 350:178-81.
Gay R, Ilharreborde B, Zhao K, Berglund L, Bronfort G, An K Stress in lumbar intervertebral discs during distraction: a cadaveric study. The Spine Journal 2007; Nov ahead of print.
Gilbert K, Brismee J, Collins D, James C, Shah R, Sawyer S, Sizer P 2006 Young investigator award winner: lumbosacral nerve root displacement and strain. Spine 2007;32:1521-5.
Griffith J, Wang Y, Antonio G, Choi K, Yu A, Ahuja A, Leung P Modified pfirrmann grading system for lumbar intervertebral disc degeneration. Spine 2007;32:E708-12.
Groen R, Gobbelaar M, Muller C, Solinge G, Verhoof O, Toit D, Hoogland P Morphology of the human internal vertebral venous plexus: a cadaver study after latex injection in the 21-25 week fetus. Clinical Anatomy 2005;18:397-403.
Gruber H, Ashraf J, Williams C, Norton H, Gordon B, Hanley E Vertebral endplate architecture and vascularization: application of mocro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat. Spine 2005;30:2593-2600.
Gruber H, Gordon B, Williams C, Norton J, Hanley E Vertebral endplate and disc changes in the aging sand rat lumbar spine. Spine 2007;32:2529-36.
Grunhagen T, Wilde G, Soukane D, Shirazi-Adl S, Urban J The nutrient supply and intervertebral disc metabolism. The Journal of Bone & Joint Surgery 2006;88:30-5.
Guehring T, Omlor G, Lorenz H, Engelleiter K, Richter W, Carstens C, Kroeber M Disc distraction shows evidence of regenerative potential in degenerated intervertebral discs as evaluated by protein expression, magnetic resonace imaging, and messenger ribonucleic acid expression analysis. Spine 2006;31:1658:1658-65.
Guehring T, Unglaub F, Lorenz H, Omlor, Wilke H-J, Kroeber M Intradiscl pressure measurements in normal discs, compressed discs and compressed discs treated with axial posterior disc distraction: and experimental study on the rabbit lumbar spine model. Eur Spine J 2006;15:597-604.
Guiot B, Fessler R Molecular biology of degenerative disc disease. Neurosurgery 2000;47:1034-40.
Guvencer M, Naderi S, Kiray A, Yilmaz H, Tetil S The relation between the lumbar vertebrae and the spinal nerves for far lateral spinal approaches. Journal of Clinical Neuroscience 2008; 15:192-197.
Hancock M, Maher C, Latimer J, Spindler M, McAuley J, Laslett M, Bogduk N Systematic review of tests to identify the disc, SIJ or facet joint as the source of low back pain. Eur Spine J 2007;16:1539-50.
Hangai M, Kaneoka K, Kuno S, Hinotsu S, Sakane M, Mamizuka N, Sakai S, Ochiai N Factors associated with lumbar intervertebral disc degeneration in the elderly. Spine 2007;a head of print.
Haschtmann D, Stoyanov J, Ferguson S Influence of diurnal hyperosmotic loading on the metabolism and matrix gene expression of a whole-organ intervertebral disc model. Journal of Orthopedic Research 2006;Oct:1957-66.
Haughton J Imaging Intervertebral Disc Degeneration Bone Joint Surg Am. 2006; 88: 15-20.
Haughton V Medical imaging of intervertebral disc degeneration. Spine 2004;29:2751-6.
Hauk E, Wittkowski W, Bothe H Intradural microanatomy of the nerve roots S1-S5 at their origin from the conus medullaris Laboratory investigation. Journal of Neurosugery 2008; 9:2.
Heuer F, Schmidt H, Wilke H The relation between intervertebral disc bulging and annular fiber associated strains for simple and complex loading. Journal of Biomechanics 2007 Article in press.
Heuer F, Schmitt H, Schmidt H, Claes L, Wilke H Creep associated changes in intervertebral disc bulging obtained with a laser scanning device. Clinical Biomechanics 2007;22:737-44.
Hirasawa Y, Bashir W, Smith F, Magnusson M, Pope M, Takashi K Postural changes of the dural sac in the lumbar spines of assymptomatic individuals using positional stand-up magnetic resonance imaging. Spine 2007;32:E136-40.
Huang C, Yuan T, Jackson A, Hazbun L, Fraker C, Gu W Effects of low glucose concentrations on oxygen consumption rates of intervertebral disc cells. Spine 2007;19:2063-9.
Hutton W, Malko J, Fajman W Lumbar disc volume measured by MRI: effects of bed rest, horizontal exercise, and vertical loading. Aviation, Space, and Environmental Medicine 2003;74:73-8.
Hutton W, Toribatake Y, Elmer W, Ganey T, Tomita K, Whitesides T The effect of compressive force applied to the intervertebral disc in vivo: a study of proteoglycans and collagen. Spine 1998;23:2524-37.
Iatridis J, Laible J, Krag M Influence of fixed charge density magnitude and distribution on the intervertebral disc: applications of a poroelastic and chemical electric (PEACE) model. Journal of Biomechanical Engineering 2003;125:12-24.
Iatridis J, MacLean J, Roughly P, Alini M Effects of mechanicalloading on intervertebral disc metabolism in vivo. The Journal of Bone and Joint Surgery 2006;88:41-6.
Izci Y, Gurkanlar D, Ozan H, Gonul E The morphological aspects of the lumbar plexus and roots: an anatomical study. Turkish Neurosurgery 2005;15:87-92.
Jazwinska E, Adam K Diurnal changes in stature: effects of sleep deprivation in youg men and middle-aged men. Experientia 1985;41: 1533-5.
Joahannessen W, Elliot D Effects of degeneration on the biphasic material properties of human nucleus pulposus in confined compression. Spine 2005;24:E724-9.
Johannessen W, Cloyd J, O’Connell G, Vresilovic E, Elliot D Trans-endplate nucleotomy increases deformation and creep response in axial loading. Annals of Biomedical Engineering 2006;34:687-96.
Johannsen W, Vresilovic E, Wright A, Elliot D Intervertebral disc mechanics are restored following cyclic loading and unloaded recovery. Annals of Biomedical Engineering 2004;32:70-6.
Kandel R, Hamilton D, Seguin C, Li S, Arana C, Pilliar An in vitro tissue model to study the effect of age on nucleus pulposus cells. Eur Spine J 2007;16:2166-73.
Kang J, Bohlman H Cervical disc herniation in a patient with congenital insensitivity to pain. Spine 2000;25:1726-8.
Kanlayanaphotporn R, Trott P, Williams M, Fulton I Effects of chronic low back pain, age and gender on vertical spinal creep. Ergonomics 2003;46:561-73.
Karadimas E, Siddiqui M, Smith F, Wardlaw D Positional MRI changes in supine versus sitting postures in patients with degenerative lumbar spine. 2006;19:495-500.
Kourtis D, Magnusson M, Smith F, Hadjipavlou A, Pope M Spine height and disc height changes as the effect of hyperextension using stadiometry and MRI. The Iowa Orthopaedic Journal 2004;24:65-71.
Kraemer J, Kolditz D, Gowin R Water and electrolyte content of human intervertebral discs under variable load. Spine 1985;10:69-71.
Kramer P, Newell L, Morris L, Simkin P Spinal degenerative disk disease (ddd) in female macaque monkeys: epidemiology and comparison with women. Journal of Orthopaedic Research 2002;20:399-408.
Kroeber M, Unglaub F, Guehring T, Nerlich A, Hadi T, Lotz J, Carstens C Effects of controlled dynamic disc distraction on degenerated intervertebral discs: an in vivo study on the rabbit lumbar spine model. Spine 2005;30:181-7.
Kroeber M, Unglaub F, Wang H, Schmid C, Thomsen M, Nerlich A, Richter W New in vivo animal model to create intervertebral disc degeneration and to investigate the effects of therapeutic strategies to stimulate disc regeneration. Spine 2002;27:2684-90.
Kuima M, Karppinen J, Niinimaki J, Ojala R, Haapea M, Heliovaara M, Korpelainen R, Taimela S, Natri A, Tervonen O Modic changes in endplates of lumbar vertebral bodies: prevalence and association with low back and sciatic pain among middle-aged male workers. Spine 2007;32:1116-22.
Langrana, N Kale S, Edwards T, Lee C, Kopacz K Measurement and analyses of the effects of adjacent and plate curvatures on vertebral stresses. The Spine Journal 2006; 6:267-8.
Leivseth G, Drerup B Spinal shrinkage during work in a sitting posture compared to work in a standing posture. Clinical Biomechanics 1997;12:409-18.
Little J, Khalsa P Human lumbar spine creep during cyclic and static flexion: creep rate, biomechanics, and facet joint capsule strain. Annals of Biomedical Engineering 2005;33:391-401.
Liu J, Ebraheim N, Haman S, Shafiq Q, Karkare N, Biyani A, Goal V, Woldenberg L Effect of the increase in the height of lumbar disc space on facet joitn articulation area in sagital plne. Spine 2006;31:E198-202.
Liu, N. Ebraheim, M. Robon, C. Sanford, Jr., R. Yeasting Effect of Lumbar Disc Space Narrowing and Retrolisthesis of Vertebra on the Intervertebral Foramen. The Spine Journal 2006; 6:54S-55S .
Lotz J Animal models of intervertebral disc degeneration. Spine 2004;29:2742-50.
Lundin O, Ekstrom L, Hellstrom M, Holm S, Sward L Injuries in the adolescent porcine spine exposed to mechanical compression. Spine 1998;23:2574-79.
MacLean J, Lee C, Grad S, Ito K, Alini M, Iatridis J Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo. Spine 2003;28:973-81.
Madsen R, Jensen T, Pope M, Soresnsen J, Bendix T The effect of body position and axial load on spinal canal morphology. Spine 2008;33:61-7.
Majumdar S Magnetic resonance imaging and spectroscopy of the intervertebral disc. NMR Biomed 2006;19:894-903.
Malko J, Hutton W, Fajman W An in vivo study of the changes in volume (and fluid content) of the lumbar intervertebral disc after overnight bed rest and during an 8 hour walking protocol. Journal of Spinal Disorders and Techniques 2002;15:157-63.
Maria A, Black K, Korn H, Nordin M Association between sitting and occupational LBP. Eur Spine J 2007;16:283-98.
Martin M, Boxell C, Malone D Pathophysiology of lumber disc degeneration: a review of the literature. Neurosurg Focus 2002;13:1-6.
Masuoka K, Michalek J, MacLean J, Stokes I, Iatridis Different effects of static versus cyclic compressive loading on rat intervertebral disc height and water loss in vitro. Spine 2007;32:1974-9.
McGill S Low Back Disorders;Evidence-Based Prevention and Rehabilitation. Human Kinetics 2002.
McGill S, Axler C Changes in spine height throughout 32 hours of bed rest. Arch Phys Med Rehabilitation 1996;77:1071-3.
McMillan D, Garbutt G, Adams M Effect of sustained loading on the water content of intervertebral discs: implications for disc metabolism. Ann Rheum Dis 1996;53:880-7.
Melrose J, Smith S, Little C, Moore R, Vernon-Roberts B, Fraser R Recent advances in annular pathobiology provide insights into rim-lesion mediated intervertebral disc degeneration and potential new approaches to annular repair strategies. Review. European Spine Journal 2008;17:1131-48.
Ming-Long Y, Heggeness M, Chen H, Jassawalla J, Luo Z Compressive loading at the end plate directly regulates flow and deformation of the basivertebral vein: an analytical study. Journal of Orthopaedic Surgery and Research 2006;1;1-6.
Moore R The vertebral endplate: disc degeneration, disc regeneration. European Spine Journal 2006;15:333-7.
Moore R The vertebral endplate: disc degeneration, disc regeneration. European Spine Journal 2006;15:S333-7.
Nagasako E, Oaklander A, Dworkin R Congentital insensitivity to pain: an update. Pain 2003;101:213-9.
O’Connel G, Vresilovic E, Elliot D Comparison of animals used in disc research to human lumbar disc geometry. Spine 2007;32:328-33.
O’Connell G, Johannessen W, Vresilovic E, Elliot D Human internal disc strains in axial compression measured noninvasively using magnetic resonance imaging. Spine 2007;32:25.
Ochia R, Ching R Rate dependence of hydraulic resistance in human lumbar vertebral bodies. Spine 2006;31:2569-74.
Oki S, Matsuda Y, Shibata T, Okumura H, Desaki J Morphologic differences of the vascular buds in the vertebral endplate: scanning electron microscopic study. Spine 1996;21:174-77.
Pappou I, Cammisa F, Girardi F Correlation of endplate shape on MRI and disc degeneration in surgically treated patients with degenerative disc disease and herniated nucleus pulposis. The Spine Journal 2007;7:32-8.
Park C Diurnal variation in lumbar MRI: correlation between sognal intensity, disc height and disc bulge. Yonsei Medical Journal 1997;38:8-18.
Peng B, Hao J, Hou S, Wu W, Jiang D, Fu X, Yang Y Possible pathogenesis of painful intervertrbral disc degeneration. Spine 2006;31:560-6.
Peretti F, Micalef J, Bourgeon A, Argenson C, Rabischong P Biomechanics of the lumbar spinal nerve roots and the first scral root within the intervertebral foramina. Surg Radiol Anat 1989;11:221-5.
Perlewitz T, Haughton V, Riley L, Nguyen-Minh C, George V Effect of molecular weight on the diffusion of contrast media into cartilage. Spine 1997;22:2707-10.
Pfirrmann C, Metzdorf A, Zanetti M, Hodler J, Boos N Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine 2001;26:1873-8.
Pransky G, Benjamin K, Hill-Fotouhi C, Fletcher K, Himmelstein J, Katz J Work-related outcomes in occupational low back pain: a multidimensional analysis. Spine 2002;27:864-70.
Race A, Broom N, Robertson P Effect of loading rate and hydration on the mechanical properties of the disc. Spine 2000;25:662-669.
Rajasekaran S, Babu J, Arun R, Armstrong B, Shetty A, Murugan S ISSLS Prize Winner: A study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs. Spine 2004;29:2654-67.
Roberts N, Hogg D, Whitehouse G, Dangerfield P Quantitative analysis of diurnal variation in volume and water content of lumbar intervertebral discs. Clinical Anatomy 1998;11:1-8.
Roberts S, Evans E, Kletsas D, Jaffray D, Einstein S Senescence in human intervertebral discs. Eur Spine J 2006;15:S312-6.
Roberts S, Urban J, Evans H, Eisentein S Transport properties of the human cartilage endplate in relation to its composition and calcification. Spine 1996;21:415-20.
Roughley P Biology of the intervertebral disc aging and degeneration: involvement of the extracellular matrix. Spine 2004;29:2691-9.
Sata K, Kikuchi S, Yonezawa T In vivo intradiscal pressure measurement in healthy individuals and in patients with ongoing back problems. Spine 1999;24:2468-74.
Sbriccoli P, Yousuf K, Kupershtein I, Solomonow M, Zhou B, Zhu M, Lu Y Static load repetition is a risk factor in the development of lumbar cumulative musculoskeletal disorder. Spine 2004;23:2643-53.
Schmidt H, Kettler A, Heuer F, Simon U, Claes L, Wilke H-J Intradiscal pressure, shear strain, and fiber strain in the intervertebral disc under combined loading. Spine 2007;32:748-55.
Schnake K, Putzier M, Haas N, Kandziora F Mechanical concepts for disc regeneration. Eur Spine J 2006;15:S354-60.
Schroeder Y, Wilson W, Huyghe JM, Baaijens FP Osmoviscoelestic finite element model of the intervertebral disc. Eur Spine J. 2006;15:S361-71.
Selard E, Shirazi A, Urban J Finite element study of nutrient diffusion in the human intervertebral disc. Spine 2003;28:1945-53.
Setton L, Chen J Cell mechanics and mechanobiology in the intervertebral disc. Spine 2004;29:271023.
Setton L, Chen J Mechanobiology of the intervertebral disc and relevance to disc degeneration. The Journal of Bone and Joint Surgery 2006;88:52-7.
Simunic D, Broom N, Robertson P Biomechanical factors influencing nuclear disruption of the intervertebral disc. Spine 2001;26:1223-30.
Singh A, Lu Y, Chen C, Cavanaugh J Mechanical properties of spinal nerve roots subjected to tension at different strain rates. Journal of Biomechanics 2006;39:1669-1676.
Sinha R, Shah S, Hume E, Tuan R The effect of a 5-day space flight on the immature rat spine. The Spine Journal 2002;2:239-243.
Skrzpiec D, Tarala M, Pollintine P, Dolan P, Adams M When are intervertebral discs stronger than their adjacent vertebrae? Spine 2007;32:2455-61.
Skrzypiec D, Pollintine P, Przybyla A, Adams M The internal mechanical properties of cervical intervertebral discs as revealed by stress profilometry. Eur Spine J 2007;16:1701-9.
Slade S, Keating J Unloaded movement facilitation exercise compared to no exercise or alternative therapy outcomes for people with nonspecific chronic low back pain: a systematic review. JMPT 2007;30:301-11.
Snook S, Webster B, McGorry R, Fogleman M, McCann K The reduction of chronic nonspecific low back pain through the control of early morning morning lumbar flexion: a randomized controlled trial. Spine 1998;23:2601-7.
Speltz M, Olson E, Hunt L, Pool R, Wilson J, Carlson C Equine intervertebral disk disease: a case report. Journal of Equine Veterninary Science 2006;26:413-9.
Stokes I, Iatridis J Mechanical conditions that accelerate intervertebral disc degeneration: overload versus immobilization. Spine 2004;29:2724-32.
Stothart J, McGill S Stadiometry: on measurement technique to reduce variability in spine shrinkage measurement. Clinical Biomechanics 2000;15:546-8.
Sucu HK, Gelal F Lumbar disk herniation with contralateral symptoms. Eur Spine J. 2006;15:570-4.
Sun D, Leong K A nonlinear hyperelastic mixture theory model for anisotropy, transport, and swelling of annulus fibrosis. Annals of Biomedical Engineering 2004;32:92-102.
Tampier C, Drake J, Callaghan J, McGill S Progressive disc herniationL an investigation of the mechanism using radiologic, hostochemical, and microscopic disseaction techniques on a porcine model. Spine 2007;32:2869-74.
Thompson R, Pearcy M, Barker T The mechanical effects of intervertebral disc lesions. Clinical Biomechanics 2004;19:448-55.
Torun F, Dolgun H, Tuna H, Attar A, Uz A, Erdem A Morphometric analysis of the roots and neural foramina of the lumbar vertebrae Surgical Neurology 2006; 66: 148-151.
Torun F, Tuna H, Buyukmumcu M, Caglar S, Baysefer A The lumbar roots and pedicles: a morphometric analysis and anatomical features. Journal of Clinical Neuroscience 2008; 15:895-899.
Tsantrizos A, Ito K, Aebi M, Steffen T Internal strains in healthy and degenerated lumbar intervertebral discs. Spine 2005;30:2129-37.
Tsirikos A, Haddo O, Noordeen H Spinal manifestatations in a patient with congenital insensitivity to pain. J Spinal Disord Tech 2004;17:326-30.
Ulrich J, Liebenberg E, Thuillier D, Lotz J ISSLS prize winner: repeated disc injury causes persistent inflammation. Spine 2007;32:2812-9.
Urban J, Holm S, Maroudas A, Nachemson A Nutrition of the intervertebral disk. Clinical Orthopaedics and Related Research 1977;129:102-14.
Urban J, Winlove CP Pathophysiology of the intervertebral disc and the challenges for MRI. Journal of Magnetic Resonance Imaging 2007;25:419-432.
Urban JP, Roberts S, Ralphs JR The nucleus of the intervertebral disc from development to degeneration. 2000 American Zoologist 40:53–61.
Van der Veen A, Dieen J, Nadort A, STam B, Smit T Intervertebral disc recovery after dynamic or static loading in vitro: is there a role for the endplate? Journal of Biomechanics 2007;40:2230-5.
Van der Veen A, Mullender M, Smit T, Kingma I, Van Dieen J Flow related mechanics of the intervertebral disc: the validity of an in vitro model. 2005;30;E534-9.
Vanwanseele B, Lucchinetti E, Stussi E The effects of immobilization on the characteristics of articular cartilage: current concepts and future directions. Osteoarthritis and Cartilage 2002;10:408-19.
Vernon-Roberts B, Moore R, Fraser R The natural history of age-related disc degeneration: the pathology and sequelae of tears. Spine 2007;32:2797-2804.
Videman T, Nurminen M The occurrence of anular tears and their relation to lofetime back pain history: a cadaveric study using barium sulfate discography. Spine 2004;29:2668-76.
Vrahas M, Mithoefer K, Joseph D The long-term effects of articular impaction. Clinical Orthopaedics and Related Research 2004;423:40-3.
Wang D, Jiang S, Dai L Biologic response of the intervertebral disc to static and dynamic compression in vitro. Spine 2007;32:2521-8.
Waris E, Eskelin M, Hermunen H, Kiviluoto O, Paajanen H Disc degeneration in low back pain; a 17 yr follow-up study using magnetic resonance imaging. Spine 2007;32:681-84.
Wilke H-J, Neef P, Caimi M, Hoogland T, Claes L New in vivo measurements of pressures in the intervertebral disc in daily life. Spine 1999;24:755-62.
Wisleder D, Smith M, Mosher T, Zatsiorsky V Lumbar spine mechanical response to axial compression load in vivo. Spine 2001;26:E403-9.
Yabuki S, Kikuchi S, Olmarker K, Myers R Acute effects of the nucleus pulposus on blood flow and endoneurial fluid pressure in at dorsal root ganglia. Spine 1998;23:2517-23.
Yantzer B, Freeman T, Lee W, Nichols T, Inamasu J, Guoit B, Johnson W Torsion-induced pressure distribution changes in human intervertebral discs: an in vitro study. Spine 2007;32:881-4.
Yoon S, Park J, Kim K, Li J, Attalah-Wasif E, Hutton W, Boden S ISSLS Prize Winner: LMP-1 upregulates intervertebral disc cell production of proteoglycans and BMPs in vitro and in vivo. Spine 2004;29:2603-2611.
Zhang D, Chippada U, Jordan K Effect of the structural water on the mechanical properties of collagen-like microfibrils: a molecular dynamics study. Annals of Biomedical Engineering 2007;35:1216-30.
Zhao F, Pollintine P, Hole B, Dolan P, Adams M Discogenic origins of spinal instability. Spine 2005;30:2621-30.
Zhou H, Hou S, Shang W, Wu W, Cheng Y, Mei F, Peng B A new in vivo animal model to create intervertebral disc degeneration characterized by MRI, radiography, CT/discogram, biochemistry, and histology. Spine 2007;32:864-72.
FOR TEACHERS AND EDUCATORS: these models are simply much closer to the real thing, allowing curious minds to understand more clearly the dynamic nature of intervertebral motion.



